ABSTRACT
Current outbreak of Covid 19 has made us mandatory of using hand sanitizers everywhere. The hand hygiene is now being very essential in the public. Compliance with hand hygiene recommendations is critical to reducing colonization and infection of the hands of all people. Hand hygiene is of utmost importance because it may be contaminated easily from direct contact with airborne microorganism droplets from coughs and sneezes. Particularly in situations like pandemic outbreak, it is crucial to interrupt and cut the transmission chain of the virus by the practice of proper hand sanitization. The use of hand sanitizers drastically reduce the transmission of microorganisms to patients, ultimately reducing morbidity, mortality, and costs associated with healthcare-associated infections (HCAI). It can be achieved with contact isolation and strict infection control tool like maintaining good hand hygiene in hospital settings and in public. The success of the hand sanitization solely depends on the use of effective hand disinfecting agents formulated in various types and forms such as bathl soaps, water-based or alcohol-based hand sanitizer, with the latter being widely used in hospital settings. To date, most of the effective hand sanitizer products are alcohol-based formulations containing 70%–95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. The present study correlated with the data available in Pubmed, and it will investigate the range of available hand sanitizers and their effectiveness as well as the formulation aspects, adverse effects, and recommendations to enhance the formulation efficiency and safety.